STAG3 and cancer: The Peyon's study [70] found that HPV+ cancers over-express novel testis antigens SYCP2, STAG3, and TCAM. STAG3 and SYCP2, an SYCP1 homologue, are components of the meiotic synaptonemal complex that promotes recombination, and SYCP1 expression induces formation of a synaptonemal complex-like structure.