Both the A*30:01 and A*33:01 alleles have similar amino acid sequences within peptide-binding pockets and have identical sequences at amino acid 77, which is located within an important anchor site, peptide-binding pocket F. HLA-A*33:01 has been linked to persistent hepatitis B infection (40); however, no association has been noted between malaria and these two alleles. Here, HLA-A is linked to malaria.