No significant differences were noted in median IL-6 [689 (range: 10.0–10,580) vs 510.3 pg/ml (range: 33.1–12,509), P = 0.19]; however, a significant elevation in median IL-10 was noted between cerebral malaria patients bearing the A*30:01 and A*33:01 alleles (n = 46) as compared to cerebral malaria patients with other alleles (n = 48) [1727.3 pg/ml (range: 10.0–18,871) vs 673.2 pg/ml (range: 101.5–7631), P = 0.026]. This evidence concerns the gene IL10 and cerebral malaria.