CXCL10 and myocarditis: In conclusion, we report for the first time the protective effect of IP-10 blocking strategy in treating CVB3-induced myocarditis, and demonstrate the pIP-10-AT injection as an effective means to antagonize endogenous IP-10 function, and thus suppress chemokine-directed immune inflammation and resultant myocardial injury, when therapy was applied after the onset of disease.