As the most abundant cell population in the skin after 4x infections wereSiglecF+ eosinophils, and R2 eosinophils sorted from total DECexpressed abundant mRNA for IL-4 and IL-13, we propose that eosinophils may be theprimary source of the copious IL-4 and IL-13 released by 4x skin biopsies. Here, IL4 is linked to infection.