IL1B and gout: Results of a recent multicenter phase 2 study have shown that canakinumab, a fully human anti-IL-1β monoclonal antibody, can produce rapid reductions in pain in patients with Gouty Arthritis who are unresponsive or intolerant to, or contraindicated for NSAIDs and/or colchicine, and can significantly reduce the risk of recurrent flares [24].