L1CAMwas reported to be involved in the advanced stages of tumor progression, and overexpression of L1CAM in normal and tumor cells increased cell motility and metastasis[36].Interestingly, both CHD6 and L1CAM were increased more than 4-fold in Cr(VI)transformed cells, suggesting a possible role of cell junction related genes inCr(VI) induced cell transformation. Here, L1CAM is linked to neoplasm.