The deposition of PrPSc in the neuropil and soma of neurons was similar to what was observed following infection with the DY TME agent and the other the long incubation period strains using the anti-PrP antibodies whose epitopes are located N-terminal to the HY PrPSc PK cleavage site (Figure 4, Panels G–H). This evidence concerns the gene PRNP and infection.