HSPD1 and tuberculosis: We have been developing a novel TB vaccine that is a DNA vaccine expressing mycobacterial heat shock protein 65 (HSP65) and interleukin-12 (IL-12), delivered by the hemagglutinating virus of Japan- (HVJ)- liposome or -envelope (HVJ-E) (HSP65 + IL-12/HVJ) [19–22].