CCL2 and neoplasm: Moreover, tumor cells recruit macrophages called tumor associated macrophages (TAMs) by secreting the colony stimulating factor (CSF-1), the chemokine ligand 2, 3, 4, 5, and 8 (CCL2, 3, 4, 5, and 8) and the vascular endothelial growth factor (VEGF) [16–18].