Another element that supports our conclusion that the CML/G0 cells are more differentiated than the normal G0 cells is that six genes that belong to the Polycomb Repressive Complex 1 (PRC1), respectively, SCML1, PHF1, PCGF3, CBX7, L3MBT1, and 4, and one (EPC2) belonging to the PRC2 group, are downregulated in the CML/G0 fraction (all of them apart from SCML1, with a difference in terms of relative gene expression under the twofold level, so they are not listed in Table 1). The gene discussed is SCML1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.