It has been reported that the oncogenic signaling from BCR/ABL can induce WT1 expression [38] and that while in normal mice only a few immature cells in the bone marrow express WT1, when CML is induced the percentage of bone marrow cells expressing WT1 rises considerably [39]. This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.