GINS1 and chronic myelogenous leukemia, BCR-ABL1 positive: The most striking difference is in the number of genes upregulated in the CML/G0 cells that are either involved in DNA replication (TOPO2a, RRM2, GINS1 and 2) or are part of the mitotic spindle machinery (MAP9, CETN3, ANLN, DLG7).