The most striking difference is in the number of genes upregulated in the CML/G0 cells that are either involved in DNA replication (TOPO2a, RRM2, GINS1 and 2) or are part of the mitotic spindle machinery (MAP9, CETN3, ANLN, DLG7). This evidence concerns the gene MAP9 and chronic myelogenous leukemia, BCR-ABL1 positive.