(v) Whereas normal CD34+ cells form almost entirely granulocyte/monocyte clusters and colonies in clonogenic experiments when stimulated by cytokines in the absence of erythropoietin, CML CD34+ G0 cells consistently spontaneously form a combination of GM and erythroid colonies in the absence of EPO. This evidence concerns the gene EPO and chronic myelogenous leukemia, BCR-ABL1 positive.