The WHS 12-year prospective follow-up of 26,274 initially healthy women ≥45 years showed that carriers of the KIF6 719Arg had 34% greater risk for myocardial infarction and 24% greater risk for total cardiovascular events (cardiovascular death, myocardial infarction, ischemic stroke, and revascularization procedures) than noncarriers [11]. This evidence concerns the gene KIF6 and ischemic stroke.