It was found that the HLA-A*02:07 was associated with skin lesions (OR = 2.37, P < 0.0005, Pc < 0.012) and arthritis (OR = 2.32, P = 0.002, Pc = 0.048), A*26:01 with uveitis (OR = 3.01, P < 0.0005, Pc < 0.012), and A*30:04 with vascular lesions (OR = 9.80, P < 0.0005, Pc < 0.012) and positive pathergy test (OR = 4.10, P = 0.002, Pc = 0.048). This evidence concerns the gene HLA-A and Arthritis.