Akt (protein kinase B) is a cellular serine/threonine protein kinase that has been implicated in cellular growth and survival.[1] Akt expression and activity were constitutively increased in human pituitary tumors, as compared to normal pituitary tissue,[14] suggesting a possible role for Akt in the pathogenesis of pituitary adenomas. This evidence concerns the gene AKT1 and pituitary gland adenoma.