Congenital iris abnormality can also occur in the setting of congenital glaucoma from homozygous or compound heterozygous mutations in cytochrome P450, family 1, subfamily B (CYP1B1; OMIM *601771; 2p22-p21) [10], in the setting of anterior segment mesenchymal dysgenesis due to heterozygous mutation in paired-like homeodomain transcription factor 3 (PITX3; OMIM +602669; 10q25) [11], and in the setting of anterior segment dysgenesis due to heterozygous mutation in v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog (MAF; OMIM *177075; 16q22-q23) [12]. Here, PITX3 is linked to congenital glaucoma.