Here we show that xenografts of human tumors retain DC inside the injected tumors bymeans of IL-8-mediated chemoattraction, that can also recruit DC to the malignancywhen injected in the subcutaneous connective tissue in the vicinity of the tumor.However, the same functional recombinant IL-8 that attracts DC and PMNs does notimpair the abilities of DC to induce T-cell activation and proliferation eitherin vitro or in vivo. Here, CXCL8 is linked to neoplasm.