By studying the effects of p27WT protein on the regulation of glioblastoma cell growth and motility we observed that the WT protein was able to stimulate the formation of neuron like protrusions in U87MG cells (Video S1), thus confirming our previous observation that p27 is able to control protrusion formation in 3D context [24], also in glioblastomas. This evidence concerns the gene CDKN1B and glioblastoma.