TP53 and neoplasm: The correlation between the combined-PI predictor and TP53 mutation status appeared to be significant (odds ratio 33.9 with 95% CI 4.8—1490.4, Fisher's Exact test p<0.001; Methods S1) and the combined-PI added significant information to TP53, tumor size and node status (analysis of deviance p = 0.035; AIC for model with and without combined-PI  = 149.96 and 152.41, respectively; Methods S1).