It has also been reported that oral administration of cobalt chloride, which activates HIF, ameliorates renal injury in diabetic nephropathy of SHR/NDmer-cp rats [7], and that VEGF plays an important role in capillary repair in damaged glomeruli in glomerulonephritis rats induced by injection of anti-Thy-1.1 antibody [8]. Here, VEGFA is linked to diabetic kidney disease.