Accordingly, this study hypothesized that PN inhibits pulmonary fibrosis by suppressing TNF-α and TGF-β [19, 25] with the aim of evaluating in a murine model its protective effects on bleomycin-induced pulmonary fibrosis in terms of survival rate, lung tissue histology, fibrosis score, and inflammatory cytokines. The gene discussed is TNF; the disease is pulmonary fibrosis.