TRPV1 and colitis: Recognition of TRPV1 as a multimodal nocisensor, its sensitization by a number of proinflammatory and proalgesic pathways, its upregulation under conditions of hyperalgesia and its apparent implication in experimental colitis have made this TRP channel an attractive target for novel antinociceptive and antiinflammatory drugs (Szallasi et al., 2007; Holzer, 2008a, 2008b; Voight & Kort, 2010).