FGFR2 and breast carcinoma: A more recent study using a combination of different techniques to investigate gene expression, protein levels and genomic changes involving FGFR2 in breast cancer suggested that FGFR2 levels are lower in tumour tissue than the adjacent normal breast ducts, and that in a proportion of cases, this could be attributed to LOH or methylation involving the FGFR2 locus [12].