Dopamine transporter gene 3’-untranslated region variable number tandem repeat polymorphism (DAT1 3’-UTR VNTR) could play a role in susceptibility to irritability and aberrant motor behavior.[50] Similarly serotonin transporter SERT might have a minor role in the development of psychosis and aggressive/irritable tendencies.[51] However, these findings require replication in large well-characterized cohorts. The gene discussed is SLC6A3; the disease is psychotic disorder.