BCL6 and diffuse large B-cell lymphoma: In contrast, immunoblastic DLBCL usually occurs in the context of severe immunosuppression, has a high frequency of EBV positivity (80–90%) with frequent expression of LMP-1 and EBNA-2, shows a non-germinal centre B-cell/activated B-cell phenotype (lack of expression of CD10 and BCL6, expression of CD138 and MUM1), and lacks rearrangements of BCL635 (Table 2, Table 3).