PIM1 encodes a serine-threonine kinase and is occasionally involved in DLBCL associated chromosomal translocations89; PAX5 encodes a B-cell specific transcription factor essential for B-lineage commitment and differentiation and involved in translocations in about 50% of lymphoplasmacytic lymphoma90; RhoH/TTF encodes a small GTP-binding protein belonging to the RAS superfamily and is involved in rare instances of lymphoma translocations91. The gene discussed is PAX5; the disease is diffuse large B-cell lymphoma.