Dutton et al.94 suggested that by activating NF-κB, and thereby up-regulating Bmi-1, LMP1 may contribute to the loss of B-cell identity in EBV carrying Hodkins’s lymphomas via down-regulating a series of B-cell markers (CD21/MS4A1, BLK, LY9). The gene discussed is PDLIM7; the disease is lymphoma.