Unlike PCR, in which sensitivity is affected by variations in the expression levels of the target genes in AML cells, MFC directly measures cell number and can be combined with cell sorting of selected cell populations for further characterization.5 To increase the sensitivity of LAP detection, the exploitation of 6–8 color antibody panels and uncommon markers such as CD15 and CD65 may have a positive effect.7 The gene discussed is FUT4; the disease is acute myeloid leukemia.