The sensitivity of a given APP or APP combination for general detection of infection/inflammation will depend on the generality of the response of the APP(s) in question (the consistency of the response in a high proportion of animals exposed to a range of different - relevant - types of infections and inflammatory states), the kinetics of the response (the rapidity, peak time and extent of the response) and the between-animal variation (the extent to which the significance of the response is affected by variations in pre-infection levels and in response levels between individual pigs). This evidence concerns the gene APP and infection.