CXCL12 and neoplasm: This lack of prognostic value for CXCL12 in EOC is somewhat puzzling, as this chemokine has been reported to enhance tumor cell proliferation and survival [16,18-20,44], to promote angiogenesis [17], to inhibit the host immune response [15] and to mediate resistance to hyperthermic intraperitoneal chemotherapy [45], which may favor tumor growth and spread.