Observations of fluorescently labelled lung tumor slices indicate that TIL (CD3+ cells) do interact in situ with monocytes/macrophages (CD14+ cells) and are mostly present in the stromal zone (Fig. 2B) whereas the striking paucity of TIL in the tumor mass (EpCAM+) makes frequent TIL-tumor cells interactions quite unlikely. Here, EPCAM is linked to neoplasm.