To analyse whether such allo-restricted cytotoxic T cells can inhibit tumour growth in vivo, we challenged Rag2−/−γC−/− mice s.c. intra-inguinally with EWS-FLI1+ HLA-A*0201+ A673 ET cells, followed by i.v. injection of EZH2 (n=7) or CHM1 (n=6) specific T cells 3 days later (see Materials and Methods). The gene discussed is CNMD; the disease is neoplasm.