Interestingly, some extrahepatic tumours also show upregulation of INHA and/or INHBB. INHBB was upregulated in malignant endometrial tissues (Worbs et al, 2007) and in malignant but not in benign pheochromocytomas (Salmenkivi et al, 2001). Here, INHA is linked to benign adrenal gland pheochromocytoma.