NFKB1 and epilepsy: The possible reasons for the lack of neuron-protective effect of NF-κB inhibition in our study might include (1) some NF-κB independent mechanisms might mediate the KA induced neuron loss in our epilepsy model; (2) both PDTC and DEX also could affect other signal pathways besides the NF-κB inhibition; (3) NF-κB activation in this epilepsy model might even have some protection effect on the cell death.