DNAH8 and ischemia: The rational for using verapamil to reduce myocardial infarct size includes their ability to (1) reduce oxygen demand by reducing afterload, preload and contractility; (2) enhance oxygen supply to the ischemic zone by relieving coronary vasospasm and vasocontraction, (3) prevent ischemia-induced calcium overload; (4) preserve mitochondrial structure and function [9, 10], (5) decrease the availability of calcium to stimulate ATPase, proteases and lipases [6].