PTK2 and cancer: Furthermore, several phosphate-containing proteins have been shown in many cancer cells [7] and gastric epithelial cells [8], the stimulation of tyrosine phosphorylation by several substrates correlates with increased adhesion, motility, invasion and alteration in the cytoskeleton, and overexpression and phosphorylation of focal adhesion kinase (FAK) in epithelial cells promotes adherence to Candida yeast cells [9]; however, the role of FAK and tyrosine phosphorylation in the regulation of the interaction of human corneal epithelial cells (HCECs) with F. solani has been poorly elucidated.