IGHE and asthma: IgE production is an important and perhaps essential aspect of the process leading to respiratory sensitization (Kimber and Dearman, 2002) and measurements of total and antigen-specific serum IgE levels are standard components of the clinical evaluation of asthma and rhinitis (AHRQ, 2002; Bousquet et al., 2008; Lemiere et al., 2006; Quillen and Feller, 2006; Tarlo et al., 2008).