In a small case-control study performed in Germany, after excluding cases with blood samples collected more than 90 days after gastrectomy, T4 stage, Hp-/CagA+, or borderline IgG results, all the remaining 32 non-cardia stomach adenocarcinoma cases were seropositive with H. pylori infection [24]. This evidence concerns the gene S100A8 and gastric cardia adenocarcinoma.