ANXA1 and viral infectious disease: To date, few but one report [20] referred the role of annexin 1 in viral infection, stating that infectious pancreatic necrosis virus (IPNV) infection to fish cell increased the expression of salmon annexin 1, and the increased expression of salmon annexin 1 inhibited the apoptosis of IPNV-infected cells and supported the growth of IPNV in cells.