In this study, univariate analysis identified significant associations between ALNM and twelve factors: age, multicentric disease, tumor size, vascular and lymphatic invasion, epithelial hyperplasia, necrosis, in situ carcinoma, perineural invasion, basal-like phenotype, and CK5, CK14 and EGFR expressions. The gene discussed is EGFR; the disease is in situ carcinoma.