TLR7 and systemic lupus erythematosus: In a discovery panel consisting mainly of Chinese and Korean populations, the association of 27 single-nucleotide polymorphisms (SNPs) in the TLR7-TLR8 region with SLE was examined, and a significant association of the TLR7 3' untranslated region (3' UTR) SNP, rs3853839, was identified.