To characterize the intense stromal remodeling and inflammatory infiltrate surrounding mPIN and prostate tumors in MPAKT/Hi-MYC mice, we performed immunohistochemistry for T-lymphocytes (CD-3), B-lymphocytes (B220) and macrophages (Mac-2) on prostate tissues from mice aged 5-9 weeks (Fig. 5). Here, MYC is linked to prostate neoplasm.