Interestingly, prostate tumors from Hi-MYC (n = 5) and MPAKT/Hi-MYC (n = 5) mice all showed reduced TUNEL staining after 14 days of RAD001 treatment compared to prostates from vehicle-treated animals (n = 4–5/genotype) (Fig. 9, S10). Here, MYC is linked to prostate neoplasm.