(In agreement with reports on other types of tumor, more intense CAIX labeling was present in small areas deep in the tumor, in tissue that was probably hypoxic [see 63]) The distance from the tumor edge of the NHE1 peak varied somewhat between individual profiles, so when the profiles were averaged (to give Fig 2B) the peak was somewhat flattened out. The gene discussed is SLC9A1; the disease is neoplasm.