Orthologues of the colon cancer susceptibility loci at 18q21 [4] and 11q23 [9] and the lung cancer susceptibility loci at 5p15, 6p21 and 15q25 [12]–[14], are in regions that were not tested for Sluc or Scc loci. Here, SERPINB3 is linked to malignant colon neoplasm.