The co-localizing Sluc4/Scc15 are linked to Trp53; Sluc32/Scc4 are linked to mismatch repair genes Msh2 and Msh6; and Sluc30 is linked to base pair repair gene Xrcc1. These genes are associated with both colon and lung cancer risk [62]–[66]. The gene discussed is MSH2; the disease is lung cancer.