When broken into tumour subtype, increased TXS expression was observed in 77% of adenocarcinoma (0.74 ± 0.1 tumour vs. 0.54 ± 0.08 normal, not significant, p = 0.08) and 77% of squamous cell carcinoma (0.88 ± 0.19 tumour vs. 0.5 ± 0.1 normal, p <0.05) samples screened (data not shown). The gene discussed is TBXAS1; the disease is squamous cell carcinoma.