Yu et al (2008) reported that gastric cancer cells had a higher invasive potential and activated FAK and p70/S6k phosphorylation levels. The difference between their data and our data is possibly related to the different tumour types. Other cell types may respond different to their TP expression, possibly because of different genetic profile (De Bruin et al, 2006; Bronckaers et al, 2009a, 2009b). Here, PTK2 is linked to gastric cancer.