Fibroblast growth factor receptor-1 (FGFR-1, CD331) is a high affinity receptor for basic fibroblast growth factor (bFGF, FGF2) and the signal transduction pathway induced by the bFGF/FGFR-1 interaction has an important role in stimulating tumor angiogenesis. Here, FGFR1 is linked to neoplasm.