As shown in Figure 3, compared with controls, SCGB3A2 (UGRP1) and SCGB2A1 (MGB2) mRNA expression was significantly down-regulated, whereas SCGB2A2 (MGB1) mRNA expression was markedly up-regulated, in both CRSsNP and CRSwNP with no significant difference between CRSsNP and CRSwNP. This evidence concerns the gene SCGB2A1 and chronic rhinosinusitis without nasal polyps.