We found that SCGB3A2 (UGRP1) staining intensity inversely correlated with post-operative endoscopy scores (r = -0.50 and P < 0.05 in CRSsNP; r = -0.58 and P < 0.01 in CRSwNP), overall VAS symptom scores (r = -0.54 and r = -0.47 in CRSsNP and CRSwNP group, respectively; P < 0.05 for both), and total VAS symptom scores (r = -0.53 and r = -0.46 in CRSsNP and CRSwNP group, respectively; P < 0.05 for both). The gene discussed is SCGB3A2; the disease is chronic rhinosinusitis without nasal polyps.