That disease activity was low is underscored by the low geometric mean ESR level in our cohort of RA-patients (16.2; 95% CI 14.7-17.7 mm/hr), that was not different (p = 0.17) between patients on conventional DMARDs (15.4; 95% CI 13.8-17.3 mm/hr) or those on biologicals (17.6; 95% CI 15.1-20.5 mm/hr). The gene discussed is ESR1; the disease is rheumatoid arthritis.