We next measured the production of the proinflammatory chemokines; MCP-1 and MIP-1β by PBMCs treated with LPS and anti-CD3 mAb, and observed significantly lower production of these chemokines in subjects when on OMD and TMD diets compared to pretreatment and off diet time points (Figure 6A, B). The gene discussed is CCL2; the disease is occult macular dystrophy.