OMG and experimental autoimmune encephalomyelitis: The mechanism of tolerance induction by HSC transplantation into fully myeloablated recipients was addressed by Chan et al. who demonstrated that transplantation of bone marrow genetically modified to express myelin oligodendrocyte glycoprotein (MOG) prevented the induction and progression of experimental autoimmune encephalomyelitis (EAE) and induced long-term remission of established disease [52].