For example, TXNIP (thioredoxin-interacting protein), EGR1, CBX7, HOXA9 and FOXN3 (checkpoint repressor 1) have tumor suppressor functions and are targeted by the potentially oncogenic miRNA miR-93, miR-183, miR-181b, miR-182 and miR-7. This evidence concerns the gene EGR1 and neoplasm.